TTD | Drug: D0M7TC

Drug General Information
Drug ID	D0M7TC
Former ID	DIB018774
Drug Name	agatoxin 489
Synonyms	AG 489
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539609]
Structure		Download 2D MOL
Formula	C26H47N7O2
InChI	InChI=1S/C26H47N7O2/c27-11-5-14-28-12-3-4-13-29-15-6-16-30-17-7-19-33(35)20-8-18-31-26(34)21-23-22-32-25-10-2-1-9-24(23)25/h1-2,9-10,22,28-30,32,35H,3-8,11-21,27H2,(H,31,34)
InChIKey	LIURIBSBVUMOJS-UHFFFAOYSA-N
PubChem Compound ID	131007
PubChem Substance ID	10242775, 14961043, 29309479, 53801092, 57343635, 74421214, 103929898, 104374119, 135086717, 141108956, 162219999, 162385394, 162784309, 238152506, 242645645, 242891335
Target and Pathway
Target(s)	Vanilloid receptor 1	Target Info	Blocker (channel blocker)	[527878]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Inflammatory mediator regulation of TRP channels
NetPath Pathway	IL2 Signaling Pathway
Pathway Interaction Database	Trk receptor signaling mediated by the MAPK pathway
Pathway Interaction Database	Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome	TRP channels
References
Ref 539609	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2484).
Ref 527878	An inhibitor of TRPV1 channels isolated from funnel Web spider venom. Biochemistry. 2005 Nov 29;44(47):15544-9.

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Drug Information