Drug Information

Drug General Information
Drug ID
D0M8KY
Former ID
DIB018043
Drug Name
(S)-DRF-1042
Synonyms
5(S)-(2'-hydroxyethoxy)-20(S)-camptothecin; 5(S)-(2'-hydroxyethoxy)-20(S)-CPT
Drug Type
Small molecular drug
Indication Bladder cancer [ICD9: 188; ICD10:C67] Clinical trial [543018]
Structure
Download
2D MOL
Formula
C22H20N2O6
InChI
InChI=1S/C22H20N2O6/c1-2-22(28)11-13-10-16-17-14(9-12-5-3-4-6-15(12)23-17)20(29-8-7-25)24(16)19(26)18(13)30-21(22)27/h3-6,9-10,20,25,28H,2,7-8,11H2,1H3/t20-,22-/m0/s1
InChIKey
UPAYPYZHFCRCMO-UNMCSNQZSA-N
PubChem Compound ID
91623363
PubChem Substance ID
249565941
Target and Pathway
Target(s) Toposisomerase-1 Target Info Inhibitor [543672]
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway DNA replication
Pathway Interaction Database Caspase Cascade in Apoptosis
WikiPathways Integrated Pancreatic Cancer Pathway
References
Ref 543018(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8261).
Ref 543672(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2636).

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