Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0G7KJ
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| Former ID |
DAP001184
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| Drug Name |
Diflorasone
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| Synonyms |
Diflorasona; Diflorasonum; Maxiflor; Murode; U 34865; Diflorasona [INN-Spanish]; Diflorasone (INN); Diflorasone [INN:BAN]; Diflorasonum [INN-Latin]; Murode (TN); (6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; (6alpha,11beta,16beta)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 6a,9a-difluoro-16b-methylprednisolone; 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
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| Drug Type |
Small molecular drug
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| Indication | Inflammatory and pruritic manifestations of corticosteroid responsive dermatoses [ICD10:L20-L30] | Approved | [551871] | ||
| Therapeutic Class |
Antiinflammatory Agents
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| Company |
Pharmacia And Upjohn Co
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| Structure |
|
Download2D MOL |
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| Formula |
C26H32F2O7
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| InChI |
InChI=1S/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(31)6-7-23(19,4)25(18,28)21(32)11-24(17,5)26(13,35-15(3)30)22(33)12-34-14(2)29/h6-7,9,13,17-18,20-21,32H,8,10-12H2,1-5H3/t13-,17-,18-,20-,21-,23-,24-,25-,26-/m0/s1
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| InChIKey |
BOBLHFUVNSFZPJ-JOYXJVLSSA-N
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| CAS Number |
CAS 2557-49-5
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| PubChem Compound ID | |||||
| PubChem Substance ID |
855657, 7848390, 8194611, 11466647, 11467767, 11486513, 14761903, 24894203, 29215002, 43127743, 47365371, 47589149, 47736650, 48035306, 49699029, 50019411, 50103984, 56422226, 57318190, 57654135, 71840216, 76963292, 85787968, 92125524, 92720069, 99319112, 103770528, 103914477, 104350411, 117575834, 121363195, 124799710, 126620401, 131310944, 134338429, 135030323, 136135911, 137005254, 139836966, 144115906, 144204426, 160963571, 163134097, 163835798, 164822906, 170465294, 175268136, 175611936, 178103647, 179116650
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| SuperDrug ATC ID |
D07AC10
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| SuperDrug CAS ID |
cas=002557495
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| Target and Pathway | |||||
| Target(s) | Phospholipase A2 | Target Info | Inhibitor | [536938] | |
| BioCyc Pathway | Phospholipases | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| WikiPathways | Glycerophospholipid biosynthesis | ||||
| References | |||||
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