Drug General Information
Drug ID	D01UJL
Former ID	DNC002646
Drug Name	N-Trimethyllysine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551393]
Structure		Download 2D MOL 3D MOL
Formula	C9H21N2O2+
Canonical SMILES	C[N+](C)(C)CCCCC(C(=O)O)N
InChI	1S/C9H20N2O2/c1-11(2,3)7-5-4-6-8(10)9(12)13/h8H,4-7,10H2,1-3H3/p+1/t8-/m0/s1
InChIKey	MXNRLFUSFKVQSK-QMMMGPOBSA-O
PubChem Compound ID	440121
PubChem Substance ID	8145614, 10298540, 11534265, 34882549, 36884232, 50002539, 57403298, 78432042, 104250328, 104622279, 127761927, 135073467, 136062410, 144235463, 152198898, 198975193, 226541855
Target and Pathway
Target(s)	Calmodulin	Target Info	Inhibitor	[551393]
KEGG Pathway	Ras signaling pathway
	Rap1 signaling pathway
	Calcium signaling pathway
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Phosphatidylinositol signaling system
	Oocyte meiosis
	Adrenergic signaling in cardiomyocytes
	Vascular smooth muscle contraction
	Circadian entrainment
	Long-term potentiation
	Neurotrophin signaling pathway
	Dopaminergic synapse
	Olfactory transduction
	Phototransduction
	Inflammatory mediator regulation of TRP channels
	Insulin signaling pathway
	GnRH signaling pathway
	Estrogen signaling pathway
	Melanogenesis
	Oxytocin signaling pathway
	Glucagon signaling pathway
	Salivary secretion
	Gastric acid secretion
	Alzheimer's disease
	Amphetamine addiction
	Alcoholism
	Pertussis
	Tuberculosis
	Glioma
NetPath Pathway	RANKL Signaling Pathway
	TSH Signaling Pathway
PANTHER Pathway	CCKR signaling map ST
Pathway Interaction Database	BCR signaling pathway
	p38 MAPK signaling pathway
	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
	Role of Calcineurin-dependent NFAT signaling in lymphocytes
	IL2 signaling events mediated by PI3K
	IFN-gamma pathway
	Lissencephaly gene (LIS1) in neuronal migration and development
	ErbB1 downstream signaling
	VEGFR1 specific signals
	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
	Calcium signaling in the CD4+ TCR pathway
	Signaling events mediated by VEGFR1 and VEGFR2
	Insulin-mediated glucose transport
	N-cadherin signaling events
	Cellular roles of Anthrax toxin
	Regulation of Ras family activation
	Downstream signaling in na&#xef
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	Calmodulin induced events
	Platelet degranulation
	Translocation of GLUT4 to the plasma membrane
	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
	DARPP-32 events
	eNOS activation
	Inactivation, recovery and regulation of the phototransduction cascade
	FCERI mediated Ca+2 mobilization
	Ca2+ pathway
	CREB phosphorylation through the activation of CaMKII
	Ras activation uopn Ca2+ infux through NMDA receptor
	Smooth Muscle Contraction
	VEGFR2 mediated vascular permeability
	VEGFR2 mediated cell proliferation
	RHO GTPases activate IQGAPs
	RAF/MAP kinase cascade
	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
WikiPathways	Translocation of GLUT4 to the Plasma Membrane
	Visual phototransduction
	Fc epsilon receptor (FCERI) signaling
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Signaling by the B Cell Receptor (BCR)
	Inositol phosphate metabolism
	DAG and IP3 signaling
	Opioid Signalling
	Muscle contraction
	Metabolism of nitric oxide
	Metabolism of carbohydrates
References
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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