TTD | Drug: D0F470

Drug General Information
Drug ID	D0F470
Drug Name	FP-025
Indication	Asthma [ICD9: 493; ICD10:J45]		Phase 1	[1725890]
Target and Pathway
Target(s)	MMP-12	Target Info	Inhibitor	[1725885]
NetPath Pathway	IL1 Signaling Pathway
NetPath Pathway	IL5 Signaling Pathway
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome	Collagen degradation
Reactome	Degradation of the extracellular matrix
WikiPathways	TGF beta Signaling Pathway
	Degradation of collagen
	Matrix Metalloproteinases
References
Ref 1725890	ClinicalTrials.gov (NCT02238834) Phase 1 Safety, Tolerability and Pharmacokinetics (PK) Study of FP-025 in Healthy Volunteers
Ref 1725885	Potential clinical implications of recent matrix metalloproteinase inhibitor design strategies.

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Drug Information