Target Information
Target General Infomation | |||||
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Target ID |
T25847
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Former ID |
TTDS00417
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Target Name |
Peptidyl-prolyl cis-trans isomerase B
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Gene Name |
PPIB
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Synonyms |
CYP-S1; CYPB; Cyclophilin B; PPIase; Rotamase; S-cyclophilin; SCYLP; PPIB
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Target Type |
Successful
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Disease | Dietary shortage [ICD9: 260-269; ICD10: E40-E46] | ||||
Function |
PPIases accelerate the foldingof proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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BioChemical Class |
Cis-trans-isomerases
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UniProt ID | |||||
EC Number |
EC 5.2.1.8
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Sequence |
MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRV
IFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYG ERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVR KVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE |
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Drugs and Mode of Action | |||||
Pathways | |||||
Pathway Interaction Database | Syndecan-1-mediated signaling events | ||||
PathWhiz Pathway | Retinol Metabolism | ||||
Reactome | Collagen biosynthesis and modifying enzymes | ||||
WikiPathways | Collagen biosynthesis and modifying enzymes | ||||
miR-targeted genes in muscle cell - TarBase | |||||
miR-targeted genes in lymphocytes - TarBase | |||||
miR-targeted genes in leukocytes - TarBase | |||||
miR-targeted genes in epithelium - TarBase | |||||
References |
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