Drug General Information
Drug ID
D0ZS8N
Former ID
DIB021051
Drug Name
THPG
Synonyms
(RS)-3,4,5-trihydroxyphenylglycine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540286]
Structure
Download
2D MOL
Formula
C8H9NO5
InChI
InChI=1S/C8H9NO5/c10-5-1-4(9-3-7(12)13)2-6(11)8(5)14/h1-2,9-11,14H,3H2,(H,12,13)
InChIKey
ZXXHFFMAINKZSZ-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) mGlu6 receptor Target Info Antagonist [534380]
References
Ref 540286(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3326).
Ref 534380Two phenylglycine derivatives antagonize responses to L-AP4 in ON bipolar cells of the amphibian retina. Neuropharmacology. 1997 Jan;36(1):13-20.

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