Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0ZL0Z
|
||||
| Former ID |
DNC012326
|
||||
| Drug Name |
PT-304
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Phase 3 | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H12FN3S2
|
||||
| Canonical SMILES |
C1=CC(=C(C=C1CC2=NC3=C(N=C2CC4=CC(=C(C=C4)Cl)Cl)N=C(N=C<br />3N)N)Cl)Cl
|
||||
| InChI |
1S/C20H14Cl4N6/c21-11-3-1-9(5-13(11)23)7-15-16(8-10-2-4-12(22)14(24)6-10)28-19-17(27-15)18(25)29-20(26)30-19/h1-6H,7-8H2,(H4,25,26,28,29,30)
|
||||
| InChIKey |
BQHNVQLDZHGCDH-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | HIV-1 reverse transcriptase | Target Info | Inhibitor | [2] | |
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT01007890) Prediction of Response to Neoadjuvant Chemotherapy in Women With Operable Breast Cancer. U.S. National Institutes of Health. | ||||
| REF 2 | J Med Chem. 1995 Dec 8;38(25):4929-36.Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studiesof PETT analogs. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.