| Drug General Information |
| Drug ID |
D0Z9TY
|
| Former ID |
DNC001337
|
| Drug Name |
SK549
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Target and Pathway |
| Target(s) |
Coagulation factor Xa |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Complement and coagulation cascades
|
|
PANTHER Pathway
|
Blood coagulation
|
|
Pathway Interaction Database
|
Beta2 integrin cell surface interactions
|
|
PathWhiz Pathway
|
Coagulation
|
|
Reactome
|
Extrinsic Pathway of Fibrin Clot Formation
|
|
Intrinsic Pathway of Fibrin Clot Formation
|
|
Common Pathway of Fibrin Clot Formation
|
|
Gamma-carboxylation of protein precursors
|
|
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
|
|
Removal of aminoterminal propeptides from gamma-carboxylated proteins
|
|
WikiPathways
|
Complement and Coagulation Cascades
|
|
Human Complement System
|
|
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
|
|
Blood Clotting Cascade
|
|
Formation of Fibrin Clot (Clotting Cascade)
|
| References |
| REF 1 | Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2. J Med Chem. 1999 Jul 29;42(15):2760-73. |
|---|
