Drug General Information
Drug ID	D0Z5VG
Former ID	DIB012502
Drug Name	CZ-48
Drug Type	Small molecular drug
Indication	Cancer [ICD9: 140-229; ICD10:C00-C96]		Phase 1	[522742]
Structure		Download 2D MOL 3D MOL
Formula	C23H20N2O5
CAS Number	CAS 194414-69-2
PubChem Compound ID	9887472
Target and Pathway
Target(s)	Toposisomerase-1	Target Info	Inhibitor	[525971]
NetPath Pathway	IL2 Signaling Pathway
PANTHER Pathway	DNA replication
Pathway Interaction Database	Caspase Cascade in Apoptosis
WikiPathways	Integrated Pancreatic Cancer Pathway
References
Ref 522742	ClinicalTrials.gov (NCT00947739) Phase I and Pharmacology Study of Camptothecin-20-O-Propionate Hydrate (CZ48) in Patients With Solid Tumors or Lymphoma. U.S. National Institutes of Health.
Ref 525971	Pharmacology of camptothecin esters. Ann N Y Acad Sci. 2000;922:216-23.

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