Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z5HB
|
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| Former ID |
DIB009972
|
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| Drug Name |
FH-510
|
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| Drug Type |
Small molecular drug
|
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| Indication | Psychotic disorders [ICD9: 290-299; ICD10:F20-F29] | Terminated | [1] | ||
| Company |
Taisho Pharmaceutical Co Ltd
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C22H31ClN2
|
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| Canonical SMILES |
[nH]1c2c(c3c1cccc3CCN(CCC)CCC)c(ccc2C)C.Cl
|
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| CAS Number |
CAS 139304-28-2
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Sigma(1)-type opioid receptor | Target Info | Modulator | [2], [3], [4] | |
| WikiPathways | miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002069) | ||||
| REF 2 | Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6. | ||||
| REF 3 | Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82. | ||||
| REF 4 | FH-510, a potent and selective ligand for rat brain sigma recognition sites. Eur J Pharmacol. 1993 Jul 6;238(1):89-92. | ||||
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