Drug Information

Drug General Information
Drug ID
D0Z3JC
Former ID
DIB014072
Drug Name
Dual-action antibiotics
Synonyms
Dual-action antibiotics, Roche; Ro-24-4383; Ro-24-6778
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Terminated [544794]
Company
Roche Holding AG
Structure
Download
2D MOL

3D MOL
Canonical SMILES
N12C(=O)[C@H]([C@H]1SCC(=C2C(=O)O)COC(=O)N1CCN(c2cc3n(c<br />c(c(=O)c3cc2F)C(=O)O)C2CC2)CC1)NC(=O)/C(=N\OC)/c1nc(sc1<br />)N
CAS Number
CAS 135312-05-9
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator [534005]
References
Ref 544794Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001135)
Ref 534005Mechanisms of action of cephalosporin 3'-quinolone esters, carbamates, and tertiary amines in Escherichia coli. Antimicrob Agents Chemother. 1993 Mar;37(3):559-65.

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