Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z1PA
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| Former ID |
DIB009945
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| Drug Name |
GG-818
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| Synonyms |
GI-231818; GW-1818
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| Indication | Prostate disease [ICD10:N42.9] | Investigative | [1] | ||
| Company |
Glaxo Wellcome plc
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
S(=O)(=O)(c1c(ccc(c1)CCN1CCC(c2nc(c(o2)c2ccc(cc2)F)COCC<br />(F)(F)F)CC1)OC)N
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| CAS Number |
CAS 179535-60-5
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| Target and Pathway | |||||
| Target(s) | Alpha-1A adrenergic receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| cGMP-PKG signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| AMPK signaling pathway | |||||
| Adrenergic signaling in cardiomyocytes | |||||
| Vascular smooth muscle contraction | |||||
| Salivary secretion | |||||
| PANTHER Pathway | Alpha adrenergic receptor signaling pathway | ||||
| Reactome | Adrenoceptors | ||||
| G alpha (q) signalling events | |||||
| G alpha (12/13) signalling events | |||||
| WikiPathways | Monoamine GPCRs | ||||
| Calcium Regulation in the Cardiac Cell | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Endothelin Pathways | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| AMPK Signaling | |||||
| References | |||||
| REF 1 | In situ salt screening--a useful technique for discovery support and preformulation studies. Pharm Dev Technol. 1998 May;3(2):215-23. | ||||
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