Drug Information

Drug General Information
Drug ID
D0Y6OE
Former ID
DNC000127
Drug Name
A-85380
Drug Type
Small molecular drug
Indication Discovery agent Phase 2 [521914], [540862]
Structure
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2D MOL

3D MOL
Formula
C9H12N2O
InChI
InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1
InChIKey
XKFMBGWHHBCWCD-QMMMGPOBSA-N
PubChem Compound ID
5310969
PubChem Substance ID
7978543, 11056176, 14772491, 15147064, 39340705, 57359306, 78984254, 96099920, 103250239, 103980061, 114154941, 129700800, 134339646, 135696207, 143354636, 178102110, 226971505
Target and Pathway
Target(s) Nicotinic acetylcholine receptor Target Info Agonist [535334]
References
Ref 521914ClinicalTrials.gov (NCT00397696) Evaluation of 5-[123I]-A-85380 and SPECT Imaging in Individuals With Parkinsons Disease. U.S. National Institutes of Health.
Ref 540862(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5460).
Ref 535334The therapeutic potential of nicotinic acetylcholine receptor agonists for pain control. Expert Opin Investig Drugs. 2001 Oct;10(10):1819-30.

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