Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Y6IJ
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| Former ID |
DIB004516
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| Drug Name |
Ro-48-5545
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| Synonyms |
Bridged beta lactamase inhibitors, Roche; Ro-47-5325; Ro-48-1256; Ro-48-5545; Ro-48-7953
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| Indication | Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] | Terminated | [1] | ||
| Company |
F Hoffmann-La Roche Ltd
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
N1(C(=O)[C@@H]2[C@H]1CCN2C(=O)NC1CCNCC1)S(=O)(=O)O
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| Target and Pathway | |||||
| Target(s) | Beta-lactamase | Target Info | Inhibitor | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008139) | ||||
| REF 2 | Potentiation of beta-lactams against Pseudomonas aeruginosa strains by Ro 48-1256, a bridged monobactam inhibitor of AmpC beta-lactamases. J Antimicrob Chemother. 1997 Sep;40(3):335-43. | ||||
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