Drug General Information
Drug ID
D0Y3ME
Former ID
DAP000062
Drug Name
Oxaliplatin
Synonyms
Eloxatin (TN); Medac (TN); Oxaliplatin (TN); Oxaliplatin (JAN/USAN/INN)
Drug Type
Small molecular drug
Indication Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21] Approved [537362], [542456]
Therapeutic Class
Anticancer Agents
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL

Formula
C8H14N2O4Pt
Canonical SMILES
C1CCC(C(C1)N)N.C(=O)(C(=O)[O-])[O-].[Pt+2]
InChI
1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1
InChIKey
ZROHGHOFXNOHSO-BNTLRKBRSA-L
CAS Number
CAS 61825-94-3
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:31941
SuperDrug ATC ID
L01XA03
SuperDrug CAS ID
cas=061825943
Target and Pathway
Target(s) Human DNA Target Info Modulator
References
Ref 537362The efficacy and toxicity of FOLFOX regimen (a combination of leucovorin and fluorouracil with oxaliplatin) as first-line treatment of metastatic colorectal cancer. Gan To Kagaku Ryoho. 2009 May;36(5):797-801.
Ref 542456(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7433).

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