Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Y0BZ
|
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| Former ID |
DIB003847
|
||||
| Drug Name |
PUP-1
|
||||
| Synonyms |
MMP-12 inhibitor (chronic obstryctive pulmonary disorder) Abiogen
|
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| Indication | Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] | Investigative | [1] | ||
| Company |
Abiogen Pharma SpA
|
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| Target and Pathway | |||||
| Target(s) | MMP-12 | Target Info | Inhibitor | [1] | |
| NetPath Pathway | IL1 Signaling Pathway | ||||
| IL5 Signaling Pathway | |||||
| Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | ||||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| WikiPathways | TGF beta Signaling Pathway | ||||
| Degradation of collagen | |||||
| Matrix Metalloproteinases | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1636). | ||||
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