TTD | Drug: D0XU0G

Drug General Information
Drug ID	D0XU0G
Former ID	DNC009663
Drug Name	N-(quinolin-3-yl)-6-(sulfamoylamino)hexanamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529866]
Structure		Download 2D MOL 3D MOL
Formula	C15H20N4O3S
Canonical SMILES	C1=CC=C2C(=C1)C=C(C=N2)NC(=O)CCCCCNS(=O)(=O)N
InChI	1S/C15H20N4O3S/c16-23(21,22)18-9-5-1-2-8-15(20)19-13-10-12-6-3-4-7-14(12)17-11-13/h3-4,6-7,10-11,18H,1-2,5,8-9H2,(H,19,20)(H2,16,21,22)
InChIKey	HIRQWWZRMZTUFZ-UHFFFAOYSA-N
PubChem Compound ID	44591342
Target and Pathway
Target(s)	Histone deacetylase 6	Target Info	Inhibitor	[529866]
KEGG Pathway	Alcoholism
KEGG Pathway	Viral carcinogenesis
Pathway Interaction Database	Signaling events mediated by HDAC Class II
Pathway Interaction Database	Signaling events mediated by HDAC Class I
Reactome	NOTCH1 Intracellular Domain Regulates Transcription
	Constitutive Signaling by NOTCH1 PEST Domain Mutants
	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
	Assembly of the primary cilium
WikiPathways	Ectoderm Differentiation
	Neural Crest Differentiation
	Cell Cycle
References
Ref 529866	Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. Epub 2008 Nov 27.Sulfamides as novel histone deacetylase inhibitors.
Ref 529866	Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. Epub 2008 Nov 27.Sulfamides as novel histone deacetylase inhibitors.

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Drug Information