Drug General Information
Drug ID	D0XQ8P
Former ID	DNC011972
Drug Name	2-Thiazol-5-ylmethyl-1,2-dihydro-indazol-3-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529474]
Structure		Download 2D MOL 3D MOL
Formula	C11H9N3OS
Canonical SMILES	C1=CC=C2C(=C1)C(=O)N(N2)CC3=CN=CS3
InChI	1S/C11H9N3OS/c15-11-9-3-1-2-4-10(9)13-14(11)6-8-5-12-7-16-8/h1-5,7,13H,6H2
InChIKey	KPXSUQVYEHMEMW-UHFFFAOYSA-N
PubChem Compound ID	14898745
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Inhibitor	[529474]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 529474	J Med Chem. 1991 Mar;34(3):1028-36.Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.
Ref 529474	J Med Chem. 1991 Mar;34(3):1028-36.Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.

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