Drug General Information
Drug ID	D0XB3U
Former ID	DNC006660
Drug Name	BM-573
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528239]
Structure		Download 2D MOL 3D MOL
Formula	C18H22N4O5S
Canonical SMILES	B(C1=C(N=C(C=C1)Cl)Cl)(O)O
InChI	1S/C5H4BCl2NO2/c7-4-2-1-3(6(10)11)5(8)9-4/h1-2,10-11H
InChIKey	XBBLBQZAVMHEER-UHFFFAOYSA-N
PubChem Compound ID	5312142
Target and Pathway
Target(s)	Thromboxane A2 receptor	Target Info	Inhibitor	[528239]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	Prostanoid ligand receptors
	G alpha (q) signalling events
	G alpha (12/13) signalling events
	Thromboxane signalling through TP receptor
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528239	J Med Chem. 2006 Jun 15;49(12):3701-9.Synthesis and pharmacological evaluation of novel nitrobenzenic thromboxane modulators as antiplatelet agents acting on both the alpha and beta isoforms of the human thromboxane receptor.
Ref 528239	J Med Chem. 2006 Jun 15;49(12):3701-9.Synthesis and pharmacological evaluation of novel nitrobenzenic thromboxane modulators as antiplatelet agents acting on both the alpha and beta isoforms of the human thromboxane receptor.

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