Drug Information
Drug General Information | |||||
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Drug ID |
D0X6IE
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Former ID |
DNC009157
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Drug Name |
4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529948] | ||
Structure |
Download2D MOL |
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Formula |
C13H15N3O4S2
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Canonical SMILES |
C1=CC(=CC=C1CNS(=O)(=O)C2=CC=C(C=C2)N)S(=O)(=O)N
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InChI |
1S/C13H15N3O4S2/c14-11-3-7-13(8-4-11)22(19,20)16-9-10-1-5-12(6-2-10)21(15,17)18/h1-8,16H,9,14H2,(H2,15,17,18)
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InChIKey |
HHCXOFYGBAPOJR-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Carbonic anhydrase VI | Target Info | Inhibitor | [529948] | |
Carbonic anhydrase IX | Target Info | Inhibitor | [529948] | ||
Carbonic anhydrase II | Target Info | Inhibitor | [530466] | ||
Carbonic anhydrase | Target Info | Inhibitor | [529948] | ||
Carbonic anhydrase I | Target Info | Inhibitor | [537461] | ||
NetPath Pathway | IL4 Signaling Pathway | ||||
EGFR1 Signaling Pathway | |||||
Pathway Interaction Database | HIF-1-alpha transcription factor networkcmyb_pathway:C-MYB transcription factor network | ||||
PathWhiz Pathway | Gastric Acid Production | ||||
Reactome | Reversible hydration of carbon dioxideR-HSA-1234158:Regulation of gene expression by Hypoxia-inducible Factor | ||||
Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen | |||||
Erythrocytes take up oxygen and release carbon dioxide | |||||
Reversible hydration of carbon dioxide | |||||
WikiPathways | Reversible Hydration of Carbon DioxideWP2877:Vitamin D Receptor Pathway | ||||
Reversible Hydration of Carbon Dioxide | |||||
Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon Dioxide | |||||
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide | |||||
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | |||||
References | |||||
Ref 529948 | J Med Chem. 2009 Feb 12;52(3):646-54.Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. | ||||
Ref 530466 | Bioorg Med Chem Lett. 2009 Dec 1;19(23):6649-54. Epub 2009 Oct 7.Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c. | ||||
Ref 537461 | Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. Bioorg Med Chem. 2009 Jul 15;17(14):5054-8. Epub 2009 May 30. |
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