Drug Information

Drug General Information
Drug ID
D0X5KF
Former ID
DAP000253
Drug Name
Hydrocodone
Synonyms
Bekadid; Codinovo; DICO; Dicodid; Dihydrocodeinone; Hidrocodona; Hydrocodeinonebitartrate; Hydrocodon; Hydrocodonum; Hydrocon; Hydrocone; Hydroconum; Idrocodone; Multacodin; Idrocodone [DCIT]; Anexsia (TN); Dicodid (TN); Duodin (TN); Hidrocodona [INN-Spanish]; Hycet (TN); Hycodan (TN); Hycomine (TN); Hydrocodone (INN); Hydrocodone [INN:BAN]; Hydrocodonum [INN-Latin]; Hydrokon (TN); Hydrovo (TN); Kolikodol (TN); Lorcet (TN); Lortab (TN); Mercodinone (TN); Norco (TN); Norgan (TN); Novahistex (TN); Orthoxycol (TN); Symtan (TN); Synkonin (TN); Vicodin (TN); Morphinan-6-one, 4,5alpha-epoxy-3-methoxy-17-methyl-(8CI); Morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha)-(9CI); (-)-Dihydrocodeinone; (5alpha)-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one; 3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one; 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one; 4,5.alpha.-Epoxy-3-methoxy-17-methylmorphinan-6-one; 4,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one; 6-Oxo-3-methoxy-N-methyl-4,5-epoxymorphinan
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Approved [538369], [542087]
Therapeutic Class
Analgesics
Company
Abbott Laboratories
Structure
Download
2D MOL

3D MOL
Formula
C18H21NO3
InChI
InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
InChIKey
LLPOLZWFYMWNKH-CMKMFDCUSA-N
CAS Number
CAS 125-29-1
PubChem Compound ID
5284569
PubChem Substance ID
10224, 81988, 11039352, 14922865, 14922868, 25652166, 29215221, 29215222, 39317884, 46506225, 48416090, 49993166, 50861005, 53790618, 56464100, 57359120, 96024738, 103526751, 128506821, 134337567, 134975724, 137001258, 142842433, 160865772, 160964295, 175268404, 178103660, 179296055, 184592120, 223890549, 226395283
ChEBI ID
ChEBI:5779
SuperDrug ATC ID
R05DA03
SuperDrug CAS ID
cas=000125291
Target and Pathway
Target(s) Mu-type opioid receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
Opioid Signalling
GPCR ligand binding
GPCR downstream signaling
References
Ref 538369FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 088017.
Ref 542087(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7081).

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