Drug Information
Drug General Information | |||||
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Drug ID |
D0X4SI
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Former ID |
DPR000102
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Drug Name |
RS-504393
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Drug Type |
Small molecular drug
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Company |
Roche
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Structure |
Download2D MOL |
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Formula |
C25H27N3O3
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InChI |
InChI=1S/C25H27N3O3/c1-17-8-9-22-20(16-17)25(31-24(29)27-22)11-14-28(15-12-25)13-10-21-18(2)30-23(26-21)19-6-4-3-5-7-19/h3-9,16H,10-15H2,1-2H3,(H,27,29)
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InChIKey |
ODNICNWASXKNNQ-UHFFFAOYSA-N
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CAS Number |
CAS 300816-15-3
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PubChem Compound ID | |||||
PubChem Substance ID |
14929247, 24696404, 46050378, 50112894, 79972630, 85788710, 103366079, 104024068, 134339542, 135566646, 135650944, 135698770, 136367799, 138230843, 151981512, 152258709, 152344313, 160647545, 160821210, 162023521, 162301649, 162832691, 163374671, 164023446, 172912668, 185964418, 204382744, 208265223, 223384980, 223573234, 235319579, 242059981, 249583053, 249826996, 250208962, 252059307, 252126288, 252156578, 252216233, 252436124
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Target and Pathway | |||||
Target(s) | C-C chemokine receptor type 2 | Target Info | Antagonist | [536223], [536550] | |
C-C motif chemokine 2 | Target Info | Inhibitor | [536223], [536549] | ||
KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
Chemokine signaling pathwayhsa04060:Cytokine-cytokine receptor interaction | |||||
Chemokine signaling pathway | |||||
NOD-like receptor signaling pathway | |||||
TNF signaling pathway | |||||
Chagas disease (American trypanosomiasis) | |||||
Malaria | |||||
Influenza A | |||||
Herpes simplex infection | |||||
Rheumatoid arthritis | |||||
NetPath Pathway | TCR Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
TGF_beta_Receptor Signaling Pathway | |||||
Leptin Signaling Pathway | |||||
RANKL Signaling PathwayNetPath_20:IL9 Signaling Pathway | |||||
IL5 Signaling Pathway | |||||
IL1 Signaling Pathway | |||||
TSH Signaling Pathway | |||||
TWEAK Signaling Pathway | |||||
IL4 Signaling Pathway | |||||
TNFalpha Signaling Pathway | |||||
TSLP Signaling Pathway | |||||
RANKL Signaling Pathway | |||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Defensins | |||||
Spinal Cord Injury | |||||
Peptide GPCRs | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP2865:IL1 and megakaryotyces in obesity | |||||
Activation of Genes by ATF4 | |||||
Oncostatin M Signaling Pathway | |||||
TNF alpha Signaling Pathway | |||||
TWEAK Signaling Pathway | |||||
IL-1 signaling pathway | |||||
Folate Metabolism | |||||
Vitamin B12 Metabolism | |||||
Selenium Micronutrient Network | |||||
References | |||||
Ref 536223 | Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91. | ||||
Ref 542757 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 781). | ||||
Ref 536223 | Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91. | ||||
Ref 536549 | Privileged structures: a useful concept for the rational design of new lead drug candidates. Mini Rev Med Chem. 2007 Nov;7(11):1108-19. | ||||
Ref 536550 | Beneficial or detrimental effects of carotenoids contained in food: cell culture models. Mini Rev Med Chem. 2007 Nov;7(11):1120-8. |
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