Drug Information
Drug General Information | |||||
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Drug ID |
D0X1EY
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Former ID |
DNC007313
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Drug Name |
6-iodo-4'-hydroxyflavone
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [527855] | ||
Structure |
Download2D MOL |
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Formula |
C15H9IO3
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Canonical SMILES |
C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=CC(=C3)I)O
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InChI |
1S/C15H9IO3/c16-10-3-6-14-12(7-10)13(18)8-15(19-14)9-1-4-11(17)5-2-9/h1-8,17H
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InChIKey |
IFAJNNUYROKKPW-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527855] | |
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Degradation of the extracellular matrix | |||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
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