Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0X0RJ
|
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| Former ID |
DNC010659
|
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| Drug Name |
JNJ-26529126
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [530079] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C31H33NO5
|
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| Canonical SMILES |
COC1=CC2=C(C=C1)C3=C(CCO2)C4=C(C=C(C=C4)O)OC3C5=CC=C(C=<br />C5)OCCN6CCCCC6
|
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| InChI |
1S/C31H33NO5/c1-34-24-10-12-27-28(20-24)36-17-13-26-25-11-7-22(33)19-29(25)37-31(30(26)27)21-5-8-23(9-6-21)35-18-16-32-14-3-2-4-15-32/h5-12,19-20,31,33H,2-4,13-18H2,1H3/t31-/m1/s1
|
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| InChIKey |
BHYFKQDXXVAJEL-WJOKGBTCSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Inhibitor | [530079] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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