Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W8OH
|
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| Former ID |
DIB007480
|
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| Drug Name |
SKF-96231
|
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| Drug Type |
Small molecular drug
|
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| Indication | Asthma [ICD10:J45] | Terminated | [1] | ||
| Company |
SmithKline Beecham plc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C14H14N4O2
|
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| Canonical SMILES |
c1(nc2c(c(=O)[nH]1)[nH]cn2)c1c(OCCC)cccc1
|
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| CAS Number |
CAS 119409-07-3
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Purine metabolism | ||||
| cGMP-PKG signaling pathway | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Reactome | cGMP effects | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003084) | ||||
| REF 2 | Analogue-based Drug Discovery II. Janos Fischer,C. Robin Ganellin. Page(150). | ||||
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