Drug Information

Drug General Information
Drug ID
D0W8AI
Former ID
DIB008624
Drug Name
Andromustine
Synonyms
GTx-200; SARM (hormone refractory prostate cancer), GTx; Selective androgen receptor modulator (hormone refractory prostate cancer), GTx; Selective androgen receptor modulator (hormone refractory prostate cancer), Merck & Co
Indication Prostate cancer [ICD9: 185; ICD10:C61] Investigative [1572605]
Company
GTx Inc
Target and Pathway
Target(s) Androgen receptor Target Info Modulator [1572605]
KEGG Pathway Oocyte meiosis
Pathways in cancer
Prostate cancer
NetPath Pathway EGFR1 Signaling Pathway
AndrogenReceptor Signaling Pathway
FSH Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
Nongenotropic Androgen signaling
Regulation of nuclear beta catenin signaling and target gene transcription
FOXA1 transcription factor network
Notch-mediated HES/HEY network
Reactome Nuclear Receptor transcription pathway
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways SIDS Susceptibility Pathways
Integrated Pancreatic Cancer Pathway
Prostate Cancer
Integrated Breast Cancer Pathway
Nuclear Receptors
Androgen receptor signaling pathway
References
Ref 1572605The ChEMBL database in 2017.
Ref 1572605The ChEMBL database in 2017.

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