Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0W7UO
|
||||
Former ID |
DCL000083
|
||||
Drug Name |
CGP71683A
|
||||
Synonyms |
CGP-71683A; N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide
|
||||
Drug Type |
Small molecular drug
|
||||
Company |
Servier
|
||||
Structure |
Download2D MOL |
||||
Formula |
C26H29N5O2S
|
||||
InChI |
InChI=1S/C26H29N5O2S/c27-25-22-9-3-4-10-23(22)30-26(31-25)28-16-18-12-14-19(15-13-18)17-29-34(32,33)24-11-5-7-20-6-1-2-8-21(20)24/h1-11,18-19,29H,12-17H2,(H3,27,28,30,31)
|
||||
InChIKey |
UULIGRNKXHCLQN-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
7978910, 11056881, 24739773, 29215520, 29217718, 39341734, 50416313, 57359513, 85209013, 103181545, 103465696, 103987903, 104052019, 114157903, 124892234, 129422299, 129422300, 131333926, 134338780, 134341415, 135650078, 140179814, 142325330, 163715699, 177748548, 179294236, 198970222, 226663935, 242204482, 248078644, 248094099
|
||||
Target and Pathway | |||||
Target(s) | Neuropeptide Y receptor 5 | Target Info | Antagonist | [535122], [536091], [536383] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
References | |||||
Ref 538948 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1562). | ||||
Ref 546849 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010609) | ||||
Ref 535122 | Neuropeptide Y Y(5) receptor antagonist CGP71683A: the effects on food intake and anxiety-related behavior in the rat. Eur J Pharmacol. 2001 Mar 2;414(2-3):215-24. | ||||
Ref 536091 | Neuropeptide Y induced modulation of dopamine synthesis in the striatum. Regul Pept. 2005 Jul 15;129(1-3):73-8. | ||||
Ref 536383 | Neuropeptide Y-induced enhancement of the evoked release of newly synthesized dopamine in rat striatum: mediation by Y2 receptors. Neuropharmacology. 2007 May;52(6):1396-402. Epub 2007 Feb 20. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.