Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0W2KG
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| Former ID |
DIB006953
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| Drug Name |
NT-69-L
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| Indication | Alcohol use disorders [ICD9: 303; ICD10:F10.2] | Investigative | [1] | ||
| Company |
Mayo Foundation
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
N1(C(=O)[C@@H](NC(=O)[C@@H](NC)CCCNC(=N)N)CCCCN)[C@H](C<br />(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)C(C)(C<br />)C)Cc2c3c([nH]cc3)ccc2)CCC1
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| CAS Number |
CAS 246871-37-4
|
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| Target and Pathway | |||||
| Target(s) | Neurotensin receptor type 1 | Target Info | Modulator | [1] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 309). | ||||
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