Drug Information
Drug General Information | |||||
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Drug ID |
D0W1XX
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Former ID |
DIB021138
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Drug Name |
uridine triphosphate
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Synonyms |
5'-UTP; uridine 5'-triphosphate
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539086] | ||
Structure |
Download2D MOL |
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Formula |
C9H15N2O15P3
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InChI |
InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
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InChIKey |
PGAVKCOVUIYSFO-XVFCMESISA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
3375, 584151, 831552, 833275, 833716, 841750, 855457, 7838933, 7891028, 7980869, 8027183, 8027189, 8143371, 8153844, 11335444, 11360683, 11364591, 11367153, 11369715, 11372791, 11374619, 11377877, 11461655, 11484245, 11488341, 11491411, 11492666, 11495511, 14720137, 14761469, 14932630, 17436071, 17436075, 24277146, 24277190, 24775910, 26706259, 26736753, 26737220, 26756678, 29225136, 47365080, 47662170, 47810645, 50061760, 53788170, 56312062, 56312125, 56312759, 56312760
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Target and Pathway | |||||
Target(s) | P2Y purinoceptor 2 | Target Info | Agonist | [526232] | |
P2Y4 receptor | Target Info | Agonist | [525757] | ||
P2Y11 receptor | Target Info | Agonist | [526628] | ||
P2Y purinoceptor 6 | Target Info | Agonist | [534141] | ||
NetPath Pathway | IL5 Signaling Pathway | ||||
References | |||||
Ref 525757 | ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor. Mol Pharmacol. 2000 May;57(5):926-31. | ||||
Ref 526232 | Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. J Med Chem. 2002 Jan 3;45(1):208-18. | ||||
Ref 526628 | Characterization of a Ca2+ response to both UTP and ATP at human P2Y11 receptors: evidence for agonist-specific signaling. Mol Pharmacol. 2003 Jun;63(6):1356-63. | ||||
Ref 534141 | Cloning, functional expression and tissue distribution of the human P2Y6 receptor. Biochem Biophys Res Commun. 1996 May 15;222(2):303-8. |
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