Drug Information

Drug General Information
Drug ID
D0VI7P
Former ID
DNC004071
Drug Name
PP2-Pro-Phe-N-MeHis-LVA-Ile-Amp-(O)
Indication Discovery agent Investigative [530554]
Structure
Download
2D MOL

3D MOL
Formula
C49H74N9O12P
Canonical SMILES
CCC(C)C(C(=O)NCC1=CC=CC=[N+]1[O-])NC(=O)C(CC(C(CC(C)C)N<br />C(=O)C(CC2=CN=CN2)N(C)C(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCN4<br />C(=O)CCCOP(=O)(O)O)O)C(C)C
InChI
1S/C49H74N9O12P/c1-8-33(6)44(48(64)51-29-36-18-12-13-22-58(36)66)55-45(61)37(32(4)5)27-42(59)38(24-31(2)3)53-47(63)41(26-35-28-50-30-52-35)56(7)49(65)39(25-34-16-10-9-11-17-34)54-46(62)40-19-14-21-57(40)43(60)20-15-23-70-71(67,68)69/h9-13,16-18,22,28,30-33,37-42,44,59H,8,14-15,19-21,23-27,29H2,1-7H3,(H,50,52)(H,51,64)(H,53,63)(H,54,62)(H,55,61)(H2,67,68,69)
InChIKey
KFCDLRKAUPBHBD-UHFFFAOYSA-N
PubChem Compound ID
44372200
Target and Pathway
Target(s) Renin, renal Target Info Inhibitor [530554]
KEGG Pathway Renin-angiotensin system
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 530554J Med Chem. 1991 Feb;34(2):633-42.Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys.
Ref 530554J Med Chem. 1991 Feb;34(2):633-42.Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.