Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0VD7H
|
||||
| Former ID |
DIB007585
|
||||
| Drug Name |
CL-5343
|
||||
| Synonyms |
CL-5343; Carbonic anhydrase inhibitors, Universita degli Studi di Firenze; Sulfonamide CA inhibitors, Universita degli Studi di Firenze; Sulfonamide CA inhibitors, University of Florence; Carbonic anhydrase inhibitors (cancer/epilepsy/glaucoma/obesity); Carbonic anhydrase inhibitors (cancer/epilepsy/glaucoma/obesity), University of Florence/ULS
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [1] | ||
| Company |
Universita degli Studi di Firenze
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C2H4N4O2S2
|
||||
| Canonical SMILES |
O=S(=O)(c1ccc(N[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)<br />O)O)cc1)N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase I | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | ||||
| Pathway Interaction Database | C-MYB transcription factor network | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | |||||
| Reversible hydration of carbon dioxide | |||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | |||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2597). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.