Drug General Information
Drug ID	D0V5HG
Former ID	DNC014779
Drug Name	7,8-dichloroquinoline-4-one-3-carboxylic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528489]
Structure		Download 2D MOL 3D MOL
Formula	C10H5Cl2NO3
Canonical SMILES	C1=CC(=C(C2=C1C(=O)C(=CN2)C(=O)O)Cl)Cl
InChI	1S/C10H5Cl2NO3/c11-6-2-1-4-8(7(6)12)13-3-5(9(4)14)10(15)16/h1-3H,(H,13,14)(H,15,16)
InChIKey	HVXHDYSWCHQWBD-UHFFFAOYSA-N
PubChem Compound ID	693139
Target and Pathway
Target(s)	Casein kinase II, alpha chain	Target Info	Inhibitor	[528489]
KEGG Pathway	Ribosome biogenesis in eukaryotes
	NF-kappa B signaling pathway
	Wnt signaling pathway
	Adherens junction
	Tight junction
	Measles
	Herpes simplex infection
	Epstein-Barr virus infection
NetPath Pathway	FSH Signaling Pathway
Pathway Interaction Database	BCR signaling pathway
	Atypical NF-kappaB pathway
	DNA-PK pathway in nonhomologous end joining
	Presenilin action in Notch and Wnt signaling
	Role of Calcineurin-dependent NFAT signaling in lymphocytes
	E-cadherin signaling in the nascent adherens junction
	Lissencephaly gene (LIS1) in neuronal migration and development
	PDGFR-alpha signaling pathway
	Signaling mediated by p38-alpha and p38-beta
	Alpha-synuclein signaling
Reactome	Condensation of Prometaphase Chromosomes
WikiPathways	Mitotic Prometaphase
	BDNF signaling pathway
	TNF alpha Signaling Pathway
	L1CAM interactions
References
Ref 528489	J Med Chem. 2006 Nov 2;49(22):6443-50.Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2.
Ref 528489	J Med Chem. 2006 Nov 2;49(22):6443-50.Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2.

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