Drug General Information
Drug ID
D0V5FQ
Former ID
DIB005116
Drug Name
Axitirome
Synonyms
CGP-26214; CGS-25845; CGS-26214
Drug Type
Small molecular drug
Indication Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78] Phase 1 [544305]
Company
Novartis AG
Structure
Download
2D MOL

3D MOL

Formula
C25H24FNO6
Canonical SMILES
c1(C(c2ccc(cc2)F)O)c(ccc(Oc2c(cc(NC(=O)C(=O)OCC)cc2C)C)<br />c1)O
CAS Number
CAS 156740-57-7
PubChem Compound ID
Target and Pathway
Target(s) Thyroid hormone receptor beta-1 Target Info Modulator [544305]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear Receptors
References
Ref 544305Bacterial biosensors for screening isoform-selective ligands for human thyroid receptors alpha-1 and beta-1. FEBS Open Bio. 2012; 2: 247-253.
Ref 544305Bacterial biosensors for screening isoform-selective ligands for human thyroid receptors alpha-1 and beta-1. FEBS Open Bio. 2012; 2: 247-253.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.