Drug Information

Drug General Information
Drug ID
D0V4NQ
Former ID
DNC002420
Drug Name
S-Ethylisothiourea
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C3H9BrN2S
Canonical SMILES
CCSC(=N)N.Br
InChI
1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H
InChIKey
SWXXKWPYNMZFTE-UHFFFAOYSA-N
CAS Number
CAS 2986-20-1
PubChem Compound ID
200213
PubChem Substance ID
542880, 607921, 10263850, 14916396, 17405054, 24278413, 24858179, 26612797, 26747505, 26758683, 33519656, 50027114, 50106269, 53777597, 56463506, 57399238, 77087887, 87569473, 89365359, 92304052, 104427846, 117385775, 118195731, 123096438, 125334768, 131389428, 135176767, 160782990, 162252864, 162283510, 162773340, 163564445, 163688160, 163739236, 175612418, 184575947, 204360396, 218911198, 224276912, 225159035, 226408203, 241181943, 251879115, 251893125, 252368855, 252469253, 252499679
Target and Pathway
Target(s) Nitric oxide synthase, inducible Target Info Inhibitor [551393]
BioCyc Pathway Citrulline-nitric oxide cycle
KEGG Pathway Arginine biosynthesis
Arginine and proline metabolism
Metabolic pathways
Calcium signaling pathway
HIF-1 signaling pathway
Peroxisome
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Tuberculosis
Pathways in cancer
Small cell lung cancer
NetPath Pathway IL1 Signaling Pathway
IL2 Signaling Pathway
Pathway Interaction Database IL12-mediated signaling events
Alpha9 beta1 integrin signaling events
ATF-2 transcription factor network
IL23-mediated signaling events
Signaling mediated by p38-alpha and p38-beta
HIF-1-alpha transcription factor network
Reactome ROS production in response to bacteria
Nitric oxide stimulates guanylate cyclase
WikiPathways Type II interferon signaling (IFNG)
Spinal Cord Injury
AGE/RAGE pathway
Effects of Nitric Oxide
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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