Drug Information

Drug General Information
Drug ID
D0V4LG
Former ID
DIB010266
Drug Name
RS-8891
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Discontinued in Phase 1 [544648]
Company
Sankyo Co Ltd
Target and Pathway
Target(s) Renin, renal Target Info Inhibitor [551182]
KEGG Pathway Renin-angiotensin system
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 544648Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000425)
Ref 551182Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension. Hypertension Research (2006) 29, 997-1005. doi:10.1291/hypres.29.997

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