Drug Information
Drug General Information | |||||
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Drug ID |
D0V3WQ
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Former ID |
DIB010349
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Drug Name |
Sch-207758
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Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Terminated | [547062] | ||
Company |
Schering-Plough Corp
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Structure |
Download2D MOL |
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Canonical SMILES |
c12c3c([nH]cc3C)c(cc2CCc2c([C@@H]1C1CCN(C(=O)Cc3cc[n+](<br />[O-])cc3)CC1)nccc2)Cl
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CAS Number |
CAS 410074-09-8
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Target and Pathway | |||||
Target(s) | Protein farnesyltransferase beta subunit | Target Info | Inhibitor | [526408] | |
NetPath Pathway | TSH Signaling Pathway | ||||
WikiPathways | Visual phototransduction | ||||
References | |||||
Ref 526408 | Exploring the role of bromine at C(10) of (+)-4-[2-[4-(8-chloro-3,10-dibromo- 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(R)-yl)-1-piperidinyl]-2- oxoethyl]-1-piperidinecarboxamide (Sch-66336): the discovery of indolocycloheptapyridine inhibitors of farnesyl protein transferase. J Med Chem. 2002 Aug 29;45(18):3854-64. |
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