Drug General Information
Drug ID
D0V2KR
Former ID
DIB007182
Drug Name
Yttrium (90Y) clivatuzumab tetraxetan
Synonyms
PAM4 mAb; Yttrium Y 90 clivatuzumab tetraxetan; Anti-MUC1 PAM4 monoclonal antibody; Clivatuzumab tetraxetan-[90Y]; HPAM4-Cide; IMMU-107; PAM-4; PAM4-Y-90; Yttrium-90-hPAM4; 90Y-clivatuzumab tetraxetan; 90Y-hPAM4
Drug Type
Antibody
Indication Pancreatic cancer [ICD9: 140-199, 140-229, 157, 210-229; ICD10:C25] Phase 3 [524457], [542962]
Company
Immunomedics; Garden State Cancer Center; Immunomedics
Target and Pathway
Target(s) Mucin 1 Target Info [551008]
WikiPathways Hematopoietic Stem Cell Differentiation
References
Ref 524457ClinicalTrials.gov (NCT01956812) Phase 3 Trial of 90Y-Clivatuzumab Tetraxetan & Gemcitabine vs Placebo & Gemcitabine in Metastatic Pancreatic Cancer. U.S. National Institutes of Health.
Ref 542962(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8087).
Ref 551008Clinical pipeline report, company report or official report of Immunomedics.

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