Drug Information

Drug General Information
Drug ID
D0U9QU
Former ID
DNAP001566
Drug Name
Ibopamine hci
Synonyms
Inopamil (TN); Scandine (TN)
Drug Type
Small molecular drug
Indication Cardiotonic [ICD10:I50] Approved [551871]
Structure
Download
2D MOL

3D MOL
Formula
C17H26ClNO4
Canonical SMILES
CC(C)C(=O)OC1=C(C=C(C=C1)CCNC)OC(=O)C(C)C.Cl
InChI
1S/C17H25NO4.ClH/c1-11(2)16(19)21-14-7-6-13(8-9-18-5)10-15(14)22-17(20)12(3)4;/h6-7,10-12,18H,8-9H2,1-5H3;1H
InChIKey
ALIXRWKJZYLBJI-UHFFFAOYSA-N
PubChem Compound ID
156320
PubChem Substance ID
10252873, 14802549, 46232147, 48414030, 49857492, 57348263, 77133524, 96024749, 104443523, 126443418, 135112402, 137000958, 162201645, 164227398, 184529330, 198944726, 227625959, 242059418
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Modulator [533417], [536361]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 533417Ibopamine. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1988 Jul;36(1):11-31.
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.

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