Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U9NY
|
||||
| Former ID |
DAP001436
|
||||
| Drug Name |
Ultracet
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Approved | [1] | ||
| Therapeutic Class |
Analgesics
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C8H9NO2
|
||||
| Canonical SMILES |
CC(=O)NC1=CC=C(C=C1)O
|
||||
| InChIKey |
RZVAJINKPMORJF-UHFFFAOYSA-N
|
||||
| CAS Number |
CAS 147630-09-9
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
9023, 70391, 408305, 609360, 3131814, 4266416, 5199969, 7847284, 7890920, 7978634, 8149184, 8151363, 10321115, 10502811, 11112253, 11114188, 11335835, 11361074, 11362770, 11365332, 11367894, 11371386, 11373699, 11376056, 11462046, 11466896, 11468016, 11483746, 11486572, 11487901, 11490099, 11491955, 11493830, 11532417, 15321628, 17390068, 17436465, 22388563, 24714721, 24715004, 24890717, 24890930, 24891173, 24891200, 26512241, 26611588, 26679279, 26697092, 26747171, 26752236
|
||||
| Target and Pathway | |||||
| Target(s) | Sodium-dependent noradrenaline transporter | Target Info | Inhibitor | [2] | |
| Sodium-dependent serotonin transporter | Target Info | Inhibitor | [2] | ||
| KEGG Pathway | Serotonergic synapse | ||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway | ||||
| 5HT2 type receptor mediated signaling pathway | |||||
| 5HT3 type receptor mediated signaling pathway | |||||
| 5HT4 type receptor mediated signaling pathway | |||||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | ||||
| WikiPathways | Monoamine Transport | ||||
| NRF2 pathway | |||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport | |||||
| SIDS Susceptibility Pathways | |||||
| Synaptic Vesicle Pathway | |||||
| Serotonin Transporter Activity | |||||
| References | |||||
| REF 1 | The Diversion of Ultram, Ultracet, and generic tramadol HCL. J Addict Dis. 2006;25(2):53-8. | ||||
| REF 2 | Augmentation effect of combination therapy of aripiprazole and antidepressants on forced swimming test in mice. Psychopharmacology (Berl). 2009 Jun 11. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.