| Drug General Information |
| Drug ID |
D0U6BT
|
| Former ID |
DNC002686
|
| Drug Name |
Rolicyclidine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C16H23N
|
| Canonical SMILES |
C1CCC(CC1)(C2=CC=CC=C2)N3CCCC3
|
| InChI |
1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2
|
| InChIKey |
FYOWWXMGDATDQY-UHFFFAOYSA-N
|
| CAS Number |
CAS 2201-39-0
|
| PubChem Compound ID |
|
| PubChem Substance ID |
5327729, 8188054, 14994553, 29216146, 43119553, 46507433, 50374060, 57314692, 104222398, 104325781, 127918242, 135021284, 137001268, 144205385, 160698767, 160964794, 163414450, 179323447, 198968994, 226830378, 250065469
|
| Target and Pathway |
| Target(s) |
D(2) dopamine receptor |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Rap1 signaling pathway
|
|
cAMP signaling pathway
|
|
Neuroactive ligand-receptor interaction
|
|
Gap junction
|
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Dopaminergic synapse
|
|
Parkinson's disease
|
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Cocaine addiction
|
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Alcoholism
|
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PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
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Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
|
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Dopamine receptor mediated signaling pathway
|
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Nicotine pharmacodynamics pathway
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Reactome
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Dopamine receptors
|
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G alpha (i) signalling events
|
|
WikiPathways
|
Hypothetical Network for Drug Addiction
|
|
Monoamine GPCRs
|
|
GPCRs, Class A Rhodopsin-like
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Genes and (Common) Pathways Underlying Drug Addiction
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GPCR ligand binding
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GPCR downstream signaling
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|
Nicotine Activity on Dopaminergic Neurons
|
| References |
| REF 1 | Leung K: 4-Acetoxy-7-chloro-3-(3-(-4-[11C]methoxybenzyl)phenyl)-2(1H)-quinolone. |
|---|
