Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U6AL
|
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| Former ID |
DIB013547
|
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| Drug Name |
BI-L-357
|
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| Synonyms |
BI-L-226
|
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| Drug Type |
Small molecular drug
|
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| Indication | Asthma [ICD10:J45] | Terminated | [1] | ||
| Company |
Boehringer Ingelheim Corp
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C18H18O4S
|
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| Canonical SMILES |
c1(c(cc(/C=C/c2sccc2)cc1C)C)OC(=O)CCC(=O)O
|
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| CAS Number |
CAS 149539-02-6
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Inhibitor | [2] | |
| BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
| Resolvin D biosynthesis | |||||
| Leukotriene biosynthesis | |||||
| Lipoxin biosynthesis | |||||
| Aspirin triggered resolvin D biosynthesis | |||||
| Aspirin triggered resolvin E biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Toxoplasmosis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002162) | ||||
| REF 2 | A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor. J Pharmacol Exp Ther. 1993 May;265(2):483-9. | ||||
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