TTD | Drug: D0U5TL

Drug General Information
Drug ID	D0U5TL
Former ID	DIB006999
Drug Name	Plavix
Synonyms	P2Y12 antagonists (thrombosis); P2Y12 antagonists (thrombosis), Pfizer
Drug Type	Small molecular drug
Indication	Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82]		Approved	[543771]
Company	Pfizer Inc
Structure		Download 2D MOL 3D MOL
Formula	C16H16ClNO2S
Canonical SMILES	C1N(CCN(C1)C(=O)[C@H](CCC(=O)O)NC(=O)c1nc(nc(c1)N1CCC(C<br />C1)C(=O)N(CC)CC)c1ccccc1)C(=O)OCCCCC
PubChem Compound ID	60606
Target and Pathway
Target(s)	P2Y purinoceptor 12	Target Info	Antagonist	[543771]
KEGG Pathway	Platelet activation
Reactome	P2Y receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543771	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 328).
Ref 543771	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 328).

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Drug Information