Drug Information
Drug General Information | |||||
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Drug ID |
D0U3EP
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Former ID |
DCL000234
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Drug Name |
SRT501
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Synonyms |
Resveratrol; Resvida; KUC104385N; R 5010; SRT 501; Cis-resveratrol; PREVENTION 8 (RESVERATROL); RM-1812; SRT-501; Trans-resveratrol; CU-01000001503-3; KSC-10-164; Resveratrol-3-sulfate; Trans-3,4',5-trihydroxystilbene; Trans-3,4′,5-Trihydroxystilbene; Trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene; (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol; (E)-5-(p-Hydroxystyryl)resorcinol; (E)-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol; (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol; (E)-resveratrol; 3,4',5-Stilbenetriol; 3,4',5-Trihydroxy-trans-stilbene; 3,4',5-Trihydroxystilbene; 3,4',5-trihydroxy-stilbene; 3,5,4'-Trihydroxy-trans-stilbene; 3,5,4'-Trihydroxystilbene; 5-((1E)-2-(4-Hydroxyphenyl)ethenyl)-1,3-benzenediol; 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol; 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol; 5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol; 5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
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Drug Type |
Small molecular drug
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Indication | Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21] | Discontinued in Phase 2 | [547718] | ||
Company |
Sirtris Pharma
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Structure |
Download2D MOL |
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Formula |
C14H12O3
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Canonical SMILES |
C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O
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InChI |
1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
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InChIKey |
LUKBXSAWLPMMSZ-OWOJBTEDSA-N
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CAS Number |
CAS 375823-41-9
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PubChem Compound ID | |||||
PubChem Substance ID |
6374, 458391, 584207, 611168, 837578, 855986, 866574, 7890614, 8145576, 10299643, 10321586, 11537676, 12015089, 14822845, 17388746, 17405667, 22388006, 24278055, 24715042, 24860876, 26512266, 26612338, 26679661, 26697115, 26736772, 26747076, 26747077, 26751586, 26751587, 26759440, 29204531, 36887952, 46386962, 46493745, 46504705, 47291249, 47515445, 47589112, 47959898, 48035263, 48035264, 48185110, 48185111, 48334633, 48424038, 48425593, 49661756, 49698529, 49734167, 49833229
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Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 1 | Target Info | Modulator | [535926] | |
BioCyc Pathway | C20 prostanoid biosynthesis | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References |
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