Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U2CV
|
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| Former ID |
DNC001459
|
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| Drug Name |
Trapidil
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Phase 4 | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C10H15N5
|
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| Canonical SMILES |
CCN(CC)C1=CC(=NC2=NC=NN12)C
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| InChI |
1S/C10H15N5/c1-4-14(5-2)9-6-8(3)13-10-11-7-12-15(9)10/h6-7H,4-5H2,1-3H3
|
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| InChIKey |
GSNOZLZNQMLSKJ-UHFFFAOYSA-N
|
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| CAS Number |
CAS 15421-84-8
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
866458, 5659229, 7848283, 8153404, 11112623, 11467040, 11468160, 11486770, 14745540, 14748788, 29224573, 47810921, 47959939, 48110614, 48259417, 49699027, 50057667, 50086436, 50100500, 56365869, 57322829, 74813390, 85787550, 88858725, 92126029, 92133451, 93815048, 103371622, 103914683, 104309497, 105640614, 117431105, 121363700, 124799773, 125432948, 126922620, 127999928, 134340574, 134340639, 134991679, 137248780, 144204129, 162249201, 162796478, 169428974, 170465770, 175612102, 178126772, 179149421, 184547380
|
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| SuperDrug ATC ID |
C01DX11
|
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| SuperDrug CAS ID |
cas=015421848
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| Target and Pathway | |||||
| Target(s) | Platelet-derived growth factor receptor | Target Info | Inhibitor | [2] | |
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT00914420) Optical Coherence Tomography (OCT) Evaluation of Re-endothelization: A Comparison of the Intrepide Stent Versus Taxus . U.S. National Institutes of Health. | ||||
| REF 2 | Osteitis fibrosa is mediated by Platelet-Derived Growth Factor-A via a phosphoinositide 3-kinase-dependent signaling pathway in a rat model for chronic hyperparathyroidism. Endocrinology. 2008 Nov;149(11):5735-46. Epub 2008 Jul 17. | ||||
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