| Drug General Information |
| Drug ID |
D0U1AN
|
| Former ID |
DNC005245
|
| Drug Name |
4-isothiocyanatobenzenesulfonamide
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C7H6N2O2S2
|
| Canonical SMILES |
C1=CC(=CC=C1N=C=S)S(=O)(=O)N
|
| InChI |
1S/C7H6N2O2S2/c8-13(10,11)7-3-1-6(2-4-7)9-5-12/h1-4H,(H2,8,10,11)
|
| InChIKey |
IMDUFDNFSJWYQT-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Carbonic anhydrase II |
Target Info |
Inhibitor |
[1]
|
|---|
| Carbonic anhydrase I |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Nitrogen metabolism
|
|
Proximal tubule bicarbonate reclamation
|
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Collecting duct acid secretion
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Gastric acid secretion
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Pancreatic secretion
|
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Bile secretionhsa00910:Nitrogen metabolism
|
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NetPath Pathway
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IL4 Signaling Pathway
|
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EGFR1 Signaling Pathway
|
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Pathway Interaction Database
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C-MYB transcription factor network
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PathWhiz Pathway
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Gastric Acid Production
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Reactome
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Erythrocytes take up carbon dioxide and release oxygen
|
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Erythrocytes take up oxygen and release carbon dioxide
|
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Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen
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Reversible hydration of carbon dioxide
|
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WikiPathways
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Reversible Hydration of Carbon Dioxide
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Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
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Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide
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Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
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| References |
| REF 1 | J Med Chem. 2004 Oct 7;47(21):5224-9.Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library. |
|---|
