Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U0ST
|
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| Former ID |
DIB020662
|
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| Drug Name |
PD159790
|
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| Synonyms |
PD-159790
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H18F3IN4
|
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| InChI |
InChI=1S/C16H18F3IN4/c1-2-24-7-3-4-11(9-24)21-14-12-8-10(20)5-6-13(12)22-15(23-14)16(17,18)19/h5-6,8,11H,2-4,7,9H2,1H3,(H,21,22,23)
|
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| InChIKey |
IRWWFCJIOHCTMV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Endothelin-converting enzyme 1 | Target Info | Inhibitor | [2] | |
| PANTHER Pathway | Endothelin signaling pathway | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Corticotropin-releasing hormone | |||||
| Endothelin Pathways | |||||
| References | |||||
| REF 1 | Evidence for intracellular endothelin-converting enzyme-2 expression in cultured human vascular endothelial cells. Circ Res. 1999 Apr 30;84(8):891-6. | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1615). | ||||
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