Drug Information
Drug General Information | |||||
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Drug ID |
D0T7BV
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Former ID |
DIB018018
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Drug Name |
compound 2
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Synonyms |
compound 37 [PMID: 22468684]
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C33H44N4O4S
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InChI |
InChI=1S/C33H44N4O4S/c1-21(40-5)29(39)37-26(16-22-8-6-9-24(14-22)31-34-12-13-42-31)28(38)20-35-27-18-33(10-7-11-33)41-30-25(27)15-23(19-36-30)17-32(2,3)4/h6,8-9,12-15,19,21,26-28,35,38H,7,10-11,16-18,20H2,1-5H3,(H,37,39)/t21-,26+,27+,28-/m1/s1
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InChIKey |
IUSARDYWEPUTPN-OZBXUNDUSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Beta-secretase | Target Info | Inhibitor | [532013] | |
References | |||||
Ref 531865 | Design and synthesis of potent, orally efficacious hydroxyethylamine derived beta-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. J Med Chem. 2012 Nov 8;55(21):9025-44. | ||||
Ref 532013 | Establishing the relationship between in vitro potency, pharmacokinetic, and pharmacodynamic parameters in a series of orally available, hydroxyethylamine-derived beta-secretase inhibitors. J Pharmacol Exp Ther. 2012 Nov;343(2):460-7. |
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