Drug General Information
Drug ID
D0T6RC
Former ID
DIB015600
Drug Name
Dihydrocodeine
Synonyms
Dihydrocodeine bitartrate; DF 118; Dihydrocodeine (oral); S-8115; Dihydrocodeine (oral), Shionogi; (-)-Dihydrocodeine
Drug Type
Small molecular drug
Indication Cancer pain [ICD9: 140-229, 338,780; ICD10:R52, G89] Phase 4 [522148], [542583]
Company
Mundipharma AG
Structure
Download
2D MOL

3D MOL

Formula
C18H23NO3
InChI
InChI=1S/C18H23NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-13,17,20H,4-5,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1
InChIKey
RBOXVHNMENFORY-DNJOTXNNSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Opioid receptor Target Info Modulator [526452]
References
Ref 522148ClinicalTrials.gov (NCT00547885) Randomized Controlled Double Blind Trial of Short vs Long Acting Dihydrocodeine in Chronic Non-malignant Pain. U.S. National Institutes of Health.
Ref 542583(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7594).
Ref 526452Affinities of dihydrocodeine and its metabolites to opioid receptors. Pharmacol Toxicol. 2002 Aug;91(2):57-63.

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