Drug General Information
Drug ID	D0T5DO
Former ID	DNC014200
Drug Name	IODOSUPROFEN
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530753]
Structure		Download 2D MOL 3D MOL
Formula	C14H11IO3S
Canonical SMILES	CC(C1=CC=C(C=C1)C(=O)C2=CC=C(S2)I)C(=O)O
InChI	1S/C14H11IO3S/c1-8(14(17)18)9-2-4-10(5-3-9)13(16)11-6-7-12(15)19-11/h2-8H,1H3,(H,17,18)
InChIKey	UIZPHGUBGPJBAR-UHFFFAOYSA-N
PubChem Compound ID	447834
Target and Pathway
Target(s)	Prostaglandin G/H synthase 1	Target Info	Inhibitor	[530753]
BioCyc Pathway	C20 prostanoid biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Platelet activation
	Serotonergic synapse
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Prostaglandin Synthesis and Regulation
	Arachidonic acid metabolism
	Phase 1 - Functionalization of compounds
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 530753	Bioorg Med Chem. 2010 Mar 15;18(6):2204-18. Epub 2010 Feb 8.In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.
Ref 530753	Bioorg Med Chem. 2010 Mar 15;18(6):2204-18. Epub 2010 Feb 8.In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.

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